1. Topological DNA damage, telomere attrition and T cell senescence during chronic viral infections.

    Ji Y, Dang X, Nguyen LNT, Nguyen LN, Zhao J, Cao D, Khanal S, Schank M, Wu XY, Morrison ZD, Zou Y, El Gazzar M, Ning S, Wang L, Moorman JP, Yao ZQ.

    Immun Ageing. 2019 Jun 24;16:12. doi: 10.1186/s12979-019-0153-z. eCollection 2019. PMID: 31285747

  1. Disruption of Telomere Integrity and DNA Repair Machineries by KML001 Induces T Cell Senescence, Apoptosis, and Cellular Dysfunctions.

    Cao D, Zhao J, Nguyan LN, Nguyen LNT, Khanal S, Dang X, Schank M, Chand Thakuri BK, Wu XY, Morrison ZD, Ei Gazzar M, Zou Y, Ning S, Wang L, Moorman JP, Yao ZQ.

    Front Immunol. 2019 May 22;10:1152. doi: 10.3389/fimmu.2019.01152. eCollection 2019. PMID: 31191531

  1. HCV-associated exosomes promote myeloid-derived suppressor cell expansion via inhibiting miR-124 to regulate T follicular cell differentiation and function.

    Wang L, Cao D, Wang L, Zhao J, Nguyen LN, Dang X, Ji Y, Wu XY, Morrison ZD, Xie Q, El Gazzar M, Ning S, Moorman JP, Yao ZQ.

    Cell Discov. 2018 Sep 11;4:51. doi: 10.1038/s41421-018-0052-z. eCollection 2018. PMID: 30210805

  1. Insufficiency of DNA repair enzyme ATM promotes naive CD4 T-cell loss in chronic hepatitis C virus infection.

    Zhao J, Dang X, Zhang P, Nguyen LN, Cao D, Wang L, Wu X, Morrison ZD, Zhang Y, Jia Z, Xie Q, Wang L, Ning S, El Gazzar M, Moorman JP, Yao ZQ.

    Cell Discov. 2018 Apr 10;4:16. doi: 10.1038/s41421-018-0015-4. eCollection 2018. PMID: 29644094

  1. Inhibition of TRF2 accelerates telomere attrition and DNA damage in naïve CD4 T cells during HCV infection.

    Nguyen LN, Zhao J, Cao D, Dang X, Wang L, Lian J, Zhang Y, Jia Z, Wu XY, Morrison Z, Xie Q, Ji Y, Zhang Z, El Gazzar M, Ning S, Moorman JP, Yao ZQ.

    Cell Death Dis. 2018 Sep 5;9(9):900. doi: 10.1038/s41419-018-0897-y. PMID: 30185784

  1. Protection of CD4+ T cells from hepatitis C virus infection-associated senescence via ΔNp63-miR-181a-Sirt1 pathway.

    Zhou Y, Li GY, Ren JP, Wang L, Zhao J, Ning SB, Zhang Y, Lian JQ, Huang CX, Jia ZS, Moorman JP, Yao ZQ.

    J Leukoc Biol. 2016 Nov;100(5):1201-1211. Epub 2016 Jun 27. PMID: 27354409

  1. Decline of miR-124 in myeloid cells promotes regulatory T-cell development in hepatitis C virus infection.

    Ren JP, Wang L, Zhao J, Wang L, Ning SB, El Gazzar M, Moorman JP, Yao ZQ.

    Immunology. 2017 Feb;150(2):213-220. doi: 10.1111/imm.12680. Epub 2016 Nov 11. PMID: 27753084

  1. Hepatitis C virus-induced myeloid-derived suppressor cells regulate T-cell differentiation and function via the signal transducer and activator of transcription 3 pathway.

    Ren JP, Zhao J, Dai J, Griffin JW, Wang L, Wu XY, Morrison ZD, Li GY, El Gazzar M, Ning SB, Moorman JP, Yao ZQ.

    Immunology. 2016 Aug;148(4):377-86. doi: 10.1111/imm.12616. Epub 2016 Jun 22. PMID: 27149428

  1. Expansion of myeloid-derived suppressor cells promotes differentiation of regulatory T cells in HIV-1+ individuals.

    Wang L, Zhao J, Ren JP, Wu XY, Morrison ZD, Elgazzar MA, Ning SB, Moorman JP, Yao ZQ.

    AIDS. 2016 Jun 19;30(10):1521-1531. doi: 10.1097/QAD.0000000000001083. PMID: 26959508

  1. MicroRNA-155 regulates interferon-γ production in natural killer cells via Tim-3 signalling in chronic hepatitis C virus infection.

    Cheng YQ, Ren JP, Zhao J, Wang JM, Zhou Y, Li GY, Moorman JP, Yao ZQ.

    Immunology. 2015 Aug;145(4):485-97. doi: 10.1111/imm.12463. Epub 2015 Apr 21. PMID: 25772938

  1. Hepatitis C virus-induced reduction in miR-181a impairs CD4(+) T-cell responses through overexpression of DUSP6.

    Li GY, Zhou Y, Ying RS, Shi L, Cheng YQ, Ren JP, Griffin JW, Jia ZS, Li CF, Moorman JP, Yao ZQ.

    Hepatology. 2015 Apr;61(4):1163-73. doi: 10.1002/hep.27634. Epub 2015 Feb 4. PMID: 25477247